Ragland followed with a short jumper, Katie Rivera scored on a layup off a feed from Ragland and Bullock nailed a layup, a three from the left side and on a put back as MWHS led 13-4 after the opening period.
Paced by 13 points from Ragland, the Lady Rams scored 24 points in the second quarter to take a 37-12 lead at the half.
Ragland continued to drive to the basket to get points and/or fouls, and she was seven-for-seven from the charity strip in the second quarter, including converting a three-point play.
Junior guard Scarlett Eaton drained a three-pointer in the period, and Valdez converted another steal into an easy two points on a layup.
The Lady Rams put the game away in the third quarter with a smothering defensive effort as Castleberry managed just four points.
Offensively, the Lady Rams continued to sizzle as they put up another 24 points, led by Ragland and Courtney Peña each with six points.
The Lady Rams continued to play tough on the defensive end in the final period as they held Castleberry to seven points to seal the game.
CHS 4 8 4 7 – 23
MWHS 13 24 24 15 – 76
MWHS – Natalie Ragland 21, Riley Bullock 10, Courtney Peña 8, Ashley Valdez 8, Scarlett Eaton 8, Kera Harrison 6, Tabby Santibanez 4, Pam Hopkins 4, Carson Couger 4, Katie Rivera 3.
Upnext: The Lady Rams will play at 6:30 p.m. Tuesday at Lake Worth.